In 1827, botanist Robert Brown noticed that while studying plant pollen under a microscope, these pieces of pollen jiggled about randomly. This motion is due to collusions of the particle with molecules of the immersion fluid. In a landmark 1905 paper, Albert Einstein predicted the existence of this microscopically-visible motion based on kinetic theory, and calculated the diffusion constant in terms of properties of the particle and the fluid in which it is immersed. Brownian motion has applications ranging from manufacturing to stock market analysis.
Some links to various Brownian motion websites: